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Scientific

Short telomeres compromise β-cell signaling and survival. Guo N, Parry EM, Li LS, Kembou F, Lauder N, Hussain MA, Berggren PO, Armanios M. PLoS One. 2011 Mar 10;6(3):e17858.

Interleukin-6 signaling in liver-parenchymal cells suppresses hepatic inflammation and improves systemic insulin action. Wunderlich FT, Ströhle P, Könner AC, Gruber S, Tovar S, Brönneke HS, Juntti-Berggren L, Li LS, van Rooijen N, Libert C, Berggren PO, Brüning JC. Cell Metab. 2010 Sep 8;12(3):237-49.

Insulin-feedback via PI3K-C2alpha activated PKBalpha/Akt1 is required for glucose-stimulated insulin secretion. Leibiger B, Moede T, Uhles S, Barker CJ, Creveaux M, Domin J, Berggren PO, Leibiger IB. FASEB J. 2010 Jun;24(6):1824-37.

A Novel Antibody Avidity Methodology for Rapid Point-of-Care Serological Diagnosis. Smolander H, Koskinen JO, Klaus Hedman, Vainionpää R, Meltola NJ, and Soini AE. Journal of Virological Methods (2010), 166(1-2): 86-91.

Simple and Rapid High-Throughput Antigen Test for High-Sensitivity Detection of Swine Influenza Virus. Koskinen JO, Vuorinen T, and Soini AE. 20th ECCMID 2010, Vienna, Austria. Poster and abstract.

Two Photon Excitation Fluorometry in Detection of Infectious Diseases. Koskinen JO. University of Turku, Ph.D. Thesis, IBN 978-951-29-3695-3, ISSN 0082-7002, Turku, Finland 2008.

Development of a Rapid Assay Methodology for Antimicrobial Susceptibility Testing of Staphylococcus Aureus. Koskinen JO, Stenholm T, Vaarno J, Soukka J, Meltola NJ, and Soini AE. Diagnostic Microbiology and Infectious Diseases (2008), 62(3):306-316.

Separation-Free Assay for Thyroid-Stimulating Hormone with Femtomolar Sensitivity. Koskinen JO, Meltola NJ, Hänninen PE, and Soini AE. Euromedlab2007, 3-7 June, 2007, Amsterdam, The Netherlands. Abstract, Clin. Chem. Lab. Med. 2007;45, Special Supplement, pp S1-S473, abstract M228 (PDF).

A Novel Separation-Free Assay Technique for Serum Antibodies Using Antibody Bridging Assay Principle and Two-Photon Excitation Fluorometry. Koskinen JO, Vaarno J, Vainiopää R, Meltola NJ, and Soini AE. Journal of Immunological Methods (2006), 309(1-2):11-24.

Dipyrrylmetheneboron Difluorides as Labels in Two-photon Excited Fluorometry. Meltola NJ. University of Turku, Ph.D. Thesis, ISBN 951-29-2955-4, Turku, Finland 2005.

Fluorescent Nanoparticles as Labels for Immunometric Assay of C-reactive Protein Using Two-Photon Excitation Assay Technology. Koskinen JO, Vaarno J, Meltola NJ, Soini JT, Hänninen PE, Luotola J, Waris ME, and Soini AE. Analytical Biochemistry. (2004), 328 (2):210-218.

Detection Methods of Microsphere Based Single-Step Bioaffinity and In-Vitro Diagnostics Assays. Soini JT, Waris ME, Hänninen PE. Journal of pharmaceutical and biomedical analysis, 34 (4): 763-770 MAR 2004 .

Syntheses of Novel Dipyrrylmethene-BF2 Dyes and Their Performance as Labels in Two-Photon Excited Fluoroimmunoassay. Meltola NJ, Soini AE, Hänninen PE. Journal of fluorescence, 14 (2): 129-138 MAR 2004.

Two-Photon Excitation Fluorometric Measurement of Homogeneous Microparticle Immunoassay for C-reactive Protein. Waris ME, Meltola NJ, Soini JT, Soini E, Peltola OJ, and Hänninen PE. Analytical biochemistry, 309 (1): 67-74 OCT 1 2002.

Two-Photon Excitation Microfluorometer for Multiplexed Single-Step Bioaffinity Assays. Soini JT, Soukka J, Soini E, and Hänninen PE. Review of scientific instruments, 73 (7): 2680-2685 Jul 2002.

Development of Instrumentation for Single-Step, Multiplexed, Microvolume Bioaffinity Assays. Soini JT. Department of Medical Physics and Chemistry, Institute of Biomedicine, University of Turku, Ph.D. Thesis, ISBN 951-29-2074-3, ISSN 0082-7002, Turku, Finland 2002.

A New Microvolume Technique for Bioaffinity Assays Using Two-Photon Excitation. Hänninen PE, Soini AE, Meltola NJ, Soini JT, Soukka J, and Soini E. Nat Biotechnol. 2000; 18(5):548-50.

Two-Photon Fluorescence Excitation in Detection of Biomolecules. Soini E, Meltola NJ, Soini AE, Soukka J, Soini JT, and Hänninen PE. Biochemical society transactions, 28: 70-74 Part 2 FEB 2000.