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mariPOC® Pharyn test for pharyngitis

The mariPOC® Pharyn test is indicated for rapid differential diagnostics of pharyngitis (or tonsillitis) causing pathogens Group A streptococcus (GAS) and adenovirus from a throat swab sample. It supports physicians in optimizing antibiotic use. Adenovirus causes similar symptoms as streptococci and mimics bacterial infections by elevating inflammation marker C-reactive protein (CRP) levels. There is no specific drug treatment for adenovirus but diagnosis enables predicting the course of the infection and reducing unnecessary use of antibiotics. GAS is the most common bacterial cause of tonsillitis and antibiotics can be used to alleviate symptoms and speedy recovery. mariPOC® is the only test in the world to combine these two most important bacterial and viral causes of pharyngitis in a single analysis.

Quick and easy sampling

mariPOC Pharyn work flow

• 15 minutes
Preliminary result with equal sensitivity to standard GAS culture.
• 55 minutes
Final result reports also low positive and negative results.

The accuracy of the GAS test exceeds the accuracy of conventional lab based culture (result time 1–2 days). This enables specific diagnosis earlier in the course of the infection and faster recovery.

Evaluation studies show that mariPOC® has an excellent sensitivity. The sensitivity level of the final results delivers almost 50% more clinically relevant and antibiotic treatable GAS infections than culture. In other words, the sensitivity of culture compared to mariPOC is about 70%.
Sampling for the test is from the throat with a flocked swab. Sample pretreatment, prior to automated analysis, is easy to do with short hands-on-time.

Test panel

mariPOC Pharyn test panel

New indication for Group A streptococci test

Indications of Group A streptococci test method now also includes perianal streptococcal dermatitis. GAS is a common cause of skin infections e.g. in perianal region. Signs and symptoms of perianal GAS infection include perianal dermatitis, itching, rectal pain, constipation and blood-streaked stools. Similar signs and symptoms are caused by, for example, irritant dermatitis, candidiasis and inflammatory bowel disease. Perianal GAS infections in children are often misdiagnosed and treated suboptimally. Untreated perianal GAS infection can persist for months and cause outbreaks in day cares and transmission among family members.