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TPX technology

What is TPX technology?

mariPOC® utilizes the ArcDiaTM TPX (Two-Photon Excitation) assay technique for highly sensitive and extremely specific direct pathogen detection. It is a proprietary technology of the Finnish Company ArcDia International Ltd., the developer and manufacturer of mariPOC®. The technology has been shown to be suitable for all applications typically performed in clinical laboratories based on immunossays or using enzyme reactions to measure clinical chemistry analytes. Potential application space in research, screening and clinical diagnostics is extremely wide.

More information about the technology

Key technological advantages

  • Separation free fluorescence measurement
  • One-step assay
  • Real-time reaction kinetics monitoring
  • Accuracy and performance independent of the reaction volume
  • Small reagent volumes and consumption
  • Compatibility with dried reagents
  • World record sensitivity and specificity
  • Wide dynamic range
  • Excellent precision

Patents

  • US 8,883,093 / JP 5716088 / RU 2568885 / CN 103068485 / BR 112012029958-1 Sealing of reaction cuvettes for bioaffinity assays
  • EP 2576059 / US 8,883,093 / JP 5716088 / RU 2568885 / CN 103068485 / BR 112012029958-1 Sealing of reaction cuvettes for bioaffinity assays
  • EP 1401962 / US 7,198,958 / JP 4382474 A method for increasing hydrophilicity of fluorescent label compounds
  • EP 1402263 / US 7,763,439 / RU 2296333 / JP 4340149 / CN 1257408 Two-photon absorbing dipyrromethene difluoride dyes and their applications

Other patents pending.

Licensing

ArcDia International Oy Ltd is interested in licensing new innovations associated with infectious disease diagnostics.

ArcDia™ TPX detection platform is also available for licensing. Ask for more information.